Where is the main switch for the cruise control in my 2001 Honda CR-V?
 

I have a bright blue indicator light burning on the dashboard to the left of the steering column. I read the owner's manual which indicates that it is the Main Cruise Control indicator Light, but I cannot see the switch that would turn it off.

I know on the 2006 it is on the left side of the steering wheel on the console. I had a 2001, can't remember though.

Try the steering wheel. There should be either a lever or a button, or both